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Clinical Cases

SLNB Breast

How are complicated sentinel lymph nodes dissected?
The search for the sentinel nodes in breast cancer patients (sentinel lymph node biopsy, SLNB) is based on your profound 3-D capabilities and the interpretation of gamma probe readings while moving over the operation site. declipseSPECT enhances your gamma probe detection capabilities and enables for the first time worldwide intraoperative 3-D imaging, 3-D high resolution image viewing and depth measurements for soft tissue targets. 3-D imaging is in direct correlation with the anatomy, enabling the guidance of surgical instruments for a direct approach to the sentinel nodes. After dissection of the sentinel lymph node the system provides a quality assurance and a tool for documentation of the complete removal of radioactive structures. Your patient is in 3-D and deserves 3-D treatment.

3-D Breast Imaging in the operation room before intervention:

  • Full 3-D image acquisition enables precise identification and localization
  • Direct correlation with anatomy provides orientation and referencing
  • Overview of activity distribution ensures detection of hidden sentinel nodes behind injection site (eliminates shadowing effects)
alt
Figure: injection site close to the nipple and two clearly visible axillary sentinels on the video image in their anatomical context

Navigation to the sentinel nodes during intervention:

  • Orientation, localization and identification in 3-D ensure safety during procedure
  • Depth measurement provides minimally invasive access
alt
Figure: activity distribution and depth measurement of sentinel nodes in 3D

Control of complete resection of all sentinel nodes:

  • Orientation, localization and identification in 3-D ensure safety during procedure
  • Documentation provides transparent and reliable follow up treatments
alt
Figure: documentation of removed activity in the axilla. No further sentinel nodes marked with Tc-99m are visible.
 

SLNB Melanoma

Where are the sentinel lymph nodes expected?
The search for the sentinel nodes in melanoma patients (sentinel lymph node biopsy, SLNB) is based on your profound orientation, 3-D capabilities, and the interpretation of gamma probe readings while moving over the operation site. The declipseSPECT solution enhances your gamma probe detection capabilities and enables for the first time worldwide intraoperative 3-D imaging, 3-D high resolution image viewing and depth measurements for soft tissue targets. 3-D imaging is in direct correlation with the anatomy, enabling the guidance of surgical instruments for a direct approach to sentinel nodes. After dissection of the sentinel lymph node the system provides a quality assurance and a tool for documentation of the complete removal of radioactive structures. Your protocol with 3-D imaging of lymph nodes in the operating room provides minimal invasiveness and direct access.

3-D Melanoma imaging in the operation room before intervention:

  • Full 3-D image acquisition ensures precise identification and localization also for sentinel nodes close to the injection site, as well as in remote areas (e.g. axilla, groin, abdominal wall, neck)
  • Direct correlation with anatomy enables orientation, referencing, and planning of minimally invasive interventions
alt
Figure: Two sentinel node conglomerates visible in its anatomical context in 3-D augmented on the real-time video image

Navigation to the sentinel nodes during intervention:

  • Orientation, localization and identification in 3-D ensures safety during procedure
  • Depth measurement provides direct and minimally invasive access
alt
Figure: Dissection of sentinel nodes using the video overlay and navigation view

Control of complete resection of all sentinel nodes:

  • 3-D scan enables confirmation of complete removal of radioactive sentinel nodes
  • Documentation provides transparent and reliable follow up treatments
alt
Figure: Documentation shows that there are no remaining sentinel nodes with radioactivity in the axilla
 

SLNB Head and Neck

Which information could support finding all lymph nodes with minimal morbidity?
The search for Sentinel Lymph Nodes in the head & neck region (sentinel lymph node biopsy, SLNB) is based on your profound orientation, 3-D capabilities, and the interpretation of gamma probe readings while moving over the operation site. The declipseSPECT solution enhances your gamma probe detection capabilities and enables for the first time worldwide intraoperative 3-D imaging, 3-D high resolution image viewing and depth measurements for soft tissue targets. 3-D imaging is in direct correlation with the anatomy, enabling guidance of surgical instruments for a direct approach to Sentinel Lymph Nodes. After dissection of the sentinel lymph node the system can provide a secondary scan which delivers a quality assurance documenting the complete removal of radioactive structures. You can perform less invasive surgery using intra-operative 3-D sentinel lymph node imaging, planning, and control during the procedure.

3-D Head and Neck imaging in the operation room before intervention:

  • Full 3-D image acquisition ensures precise identification and localization
  • Direct correlation with anatomy enables orientation and referencing
alt
Figure: 3-D imaging of sentinel nodes in the neck in a melanoma in the head. Possibility of precise planning with intra-operative 3-D imaging and visualization for a minimally invasive incision and direct removal of the sentinel node.

Navigation to the sentinel nodes during intervention:

  • Orientation, localization and identification in 3-D ensure safety during procedure
  • Depth measurement enables direct and minimally invasive access
alt
Figure: depth measurement provides valuable information for minimally invasive removal of the sentinel node through a direct access path without large trauma of surrounding tissue

Control of complete resection of all sentinel nodes

  • 3-D scan provides confirmation of complete removal of radioactive sentinel nodes
  • Documentation enables transparent and reliable follow up treatments
alt
Figure: documentation of the complete removal of sentinel nodes in the head & neck area. No further damage of the surrounding tissue due to searching for remaining radioactivity.
 

ROLL and SNOLL Breast

How can non palpable regions be safely localized and resected?
The resection of non palpable lesion using ROLL (radio-guided occult lesion localization) and its combination with SLNB (SNOLL) are challenging tasks which are based on your profound orientation, 3-D capabilities, and the interpretation of gamma probe readings while moving over the operation situs. The declipseSPECT solution enhances your gamma probe detection capabilities and enables for the first time worldwide intraoperative 3-D imaging, 3-D high resolution image viewing and depth measurements for soft tissue targets. The 3-D imaging is in direct correlation with the anatomy, enabling guidance of surgical instruments for a direct approach to the radioactive marked seeds. After dissection of the tumor mass, the system provides a scan of the area to visualize during surgery the 3-D distribution of radioactivity in the tumor mass. SurgicEye solutions support your vision of minimal invasive and residual free tumor resection by imaging the structures in all three dimensions over time.

3-D Breast Imaging in the operation room before intervention:

  • Full 3-D image acquisition enables precise identification and localization
  • Direct correlation with anatomy provides orientation and referencing
  • Overview of activity distribution ensures detection/identification of the labeled tumors, and the case of SNOLL, the injection site, and sentinel nodes, even if they are covering each other (it eliminates shadowing effects)
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Figure: 3-D image of the radioactivity distribution in palpable primary tumor for sentinel node marking and in a non palpable lesion for radio-guided occult lesion localization

Navigation to the non-palpable tumors during intervention:

  • Orientation, localization and identification in 3-D ensure safety during procedure
  • Depth measurement provides direct and minimally invasive access
alt
Figure: image overlay for correlation of the 3-D image with the anatomy of the patient.

Control of clean border resection of all non-palpable tumors:

  • 3-D scan provides confirmation of complete removal of radioactively marked tumors
  • Enables specimen examination after resection and boundary control through direct visual evaluation
  • Documentation enables transparent and reliable follow up treatments
alt
Figure: control of the specimen to confirm the seed location within it and for direct estimation of tumor borders before waiting for the pathology results
 


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